Autism Spectrum Disorder Treatment in India
Autism spectrum disorder (ASD) is a developmental disability that can cause significant social, communication and behavioral challenges. They suffer persistent challenges in social interaction, speech and nonverbal communication, and restricted/repetitive behaviors. The effects of ASD and the severity of symptoms are different in each person.
Cell therapy is preferred treatment method, which as has shown a glimmer of the possibility of altering the core pathology as well as providing symptomatic improvement in children and adults with Autism.
The rationale behind treating autism with umbilical cord tissue-derived mesenchymal stem cells is that autism, and its degree of severity, has been significantly correlated inflammatory and neuro-inflammatory cytokines including macrophage-derived chemokine (MDC) and thymus and activation-regulated chemokine (TARC). Intravenous administration of umbilical cord MSCs has been shown in multiple clinical trials to decrease inflammation. Decreasing inflammation in the autistic patient may alleviate symptoms of autism.
Stem cells have the potential to repair the affected neural tissue at the molecular, structural and functional level. Cell therapy using autologous bone marrow derived MNC’s has shown significant clinical and objective radiological improvements in children with ASD.
Expected Outcome after cell therapy are:
- Reduction in self stimulatory behavior
- Improvement in eye contact
- Improvement in speech
- Improvement in speech and communication skills
- Improvement in social interactions
- Reduction in aggressive and self‐injurious behavior
